CHOLESTEROL ESTER EXCHANGE BETWEEN HUMAN-PLASMA HIGH AND LOW-DENSITY LIPOPROTEINS MEDIATED BY A PLASMA-PROTEIN FACTOR

被引：65

作者：

SNIDERMAN, A ^{[1
]}

TENG, B ^{[1
]}

VEZINA, C ^{[1
]}

MARCEL, YL ^{[1
]}

机构：

[1] UNIV MONTREAL,CLIN RES INST,MONTREAL 101,QUEBEC,CANADA

来源：

ATHEROSCLEROSIS | 1978年 / 31卷 / 03期

基金：

英国医学研究理事会;

关键词：

Cholesterol ester exchange; Cholesterol metabolism; Higher density lipoprotein; Low density lipoprotein;

D O I：

10.1016/0021-9150(78)90067-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Although unesterified cholesterol and phospholipids exchange freely, a protein factor from the d > 1.25 g/ml plasma fraction was found to be necessary for cholesterol esters to transfer from HDL to LDL. This transfer was reversible, time-dependent and a function of the concentration of the d > 1.25 fraction, but independent of lecithin : cholesterol acyltransferase reaction. The transfer represented an equilibration of molecules, but no net mass transfer of cholesterol esters could be demonstrated from HDL to LDL. © 1978.

引用

页码：327 / 333

页数：7

共 16 条

[11]

NICHOLS AV, 1965, J LIPID RES, V6, P206

[12]

RADOLA BJ, 1973, ANN NY ACAD SCI, V209, P127, DOI 10.1111/j.1749-6632.1973.tb47523.x

[13]

SNIDERMAN A, 1975, J LIPID RES, V16, P465

[14] DETERMINATION OF LECITHIN - CHOLESTEROL ACYLTRANSFER IN HUMAN BLOOD PLASMA [J].

STOKKE, KT ;

NORUM, KR .

SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION, 1971, 27 (01) :21-&

[15]

ZAK B, 1954, ANAL CHEM, V26, P767

[16] STIMULATION OF CHOLESTEROL ESTER EXCHANGE BY LIPOPROTEIN-FREE RABBIT PLASMA [J].

ZILVERSMIT, DB ;

HUGHES, LB ;

BALMER, J .

BIOCHIMICA ET BIOPHYSICA ACTA, 1975, 409 (03) :393-398

← 1 2 →