PROMOTER-OPERATOR REGION OF LAC OPERON OF ESCHERICHIA COLI

被引：110

作者：

MILLER, JH

IPPEN, K

SCAIFE, JG

BECKWITH, JR

机构：

[1] Department of Bacteriology and Immunology, Harvard Medical School, Boston

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1968年 / 38卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0022-2836(68)90395-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Deletion mapping of the lac operon confirms the order i-p-o-z-y-a. The promoter and operator sites are substantially distinct from each other. The promoter region is shown to be essential for the expression of the lac operon; deletion of this region severely affects lac activity. The combined promoter-operator region between the i and z genes is much smaller than the average gene. © 1968.

引用

页码：413 / +

页数：1

共 25 条

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BECKWITH, JR
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[7] REGULATION OF LAC OPERON
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[8] BROWN JL, 1966, J BIOL CHEM, V241, P2826
[9] GENETIC MAPPING OF REGULATOR AND OPERATOR GENES OF LAC OPERON
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[J]. JOURNAL OF MOLECULAR BIOLOGY, 1968, 36 (03) : 413 - +
[10] REGULATION OF GENE EXPRESSION
EPSTEIN, W
BECKWITH, JR
[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1968, 37 : 411 - +

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