ANTIBACTERIAL ACTIVITIES OF NON-ANTIBIOTIC DRUGS

被引:62
作者
CEDERLUND, H
MARDH, PA
机构
[1] Institute of Clinical Bacteriology, Uppsala Univesity, S-751 22
关键词
D O I
10.1093/jac/32.3.355
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Antibacterial activities of several 'non-antibiotic drugs' used in treatment of a variety of non-infectious human diseases have been observed. Such an effect has been noticed for barbiturates, beta-adrenergic receptor antagonists, diuretic drugs, H1 antihistamines, mucolytic agents, nonsteroid anti-inflammatory drugs, proton pump inhibitors and psychotherapeutic drugs. A synergic or antagonistic effect with antibiotics of several of these drugs have also been noticed. In this overview the knowledge in the field is summarized, omitting hormones, drugs with local effects and those with low therapeutic indexes. Therapeutic implications and future considerations are discussed. © 1993 The British Society for Antimicrobial Chemotherapy.
引用
收藏
页码:355 / 365
页数:11
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