EFFECT OF BINDER AND GEOMETRY OF TABLET ON RATE OF WEAR, HARDNESS AND TENSILE-STRENGTH

被引：2

作者：

HWANG, RC

PARROTT, EL

机构：

[1] Division of Pharmaceutics, College of Pharmacy, University of Iowa, Iowa City, IA

来源：

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY | 1993年 / 19卷 / 05期

关键词：

D O I：

10.3109/03639049309062963

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The relation of concentration of starch and povidone in tablets of Emcompress and Fast-Flo lactose and the relation of pressure applied to the tablets to wear rate constant, hardness and tensile strength are reported. The extent to which these parameters are changed by concentration and applied pressure-is compared. The influence of shape on the wearability of flat face, flat face bevel edge bisect and standard convex tablets with and without a lubricant was studied.

引用

页码：507 / 519

页数：13