COMPARISON OF ONDANSETRON WITH CUSTOMARY TREATMENT IN THE PROPHYLAXIS OF NAUSEA AND EMESIS INDUCED BY NON-CISPLATIN CONTAINING CHEMOTHERAPY

被引：15

作者：

JANTUNEN, IT

FLANDER, MK

HEIKKINEN, MI

KUOPPALA, TA

TEERENHOVI, L

KATAJA, VV

机构：

[1] KUOPIO UNIV HOSP,DEPT RADIOTHERAPY,KUOPIO,FINLAND

[2] TAMPERE UNIV HOSP,KANGASALA,FINLAND

[3] OULU UNIV HOSP,OULU,FINLAND

[4] KUOPIO UNIV HOSP,DEPT ONCOL,KUOPIO,FINLAND

[5] UNIV HELSINKI,CENT HOSP,HELSINKI,FINLAND

[6] TAMPERE UNIV HOSP,DEPT GYNAECOL & OBSTET,TAMPERE,FINLAND

来源：

ACTA ONCOLOGICA | 1993年 / 32卷 / 04期

关键词：

D O I：

10.3109/02841869309093619

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

One hundred cancer patients receiving non-cisplatin containing chemotherapy were entered in a prospective study in which the efficacy of ondansetron was compared with standard antiemetic treatments in the prophylaxis of nausea and emesis. During the first 24 h, 77% of patients on ondansetron reported complete control of emesis compared with 56% of those on customary treatments (p=0.03). However, no statistically significant difference was observed between ondansetron and customary treatments in control of delayed emesis on days 2-5. Nor was any statistically significant difference seen between ondansetron and customary treatments in preventing acute or delayed nausea.

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页码：413 / 415

页数：3

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