CHROMOSOME PAINTING IN MAMMALS AS AN APPROACH TO COMPARATIVE GENOMICS

被引：73

作者：

WIENBERG, J ^{[1
]}

STANYON, R ^{[1
]}

机构：

[1] UNIV GENOA,IST ANTROPOL FIS,I-16126 GENOA,ITALY

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1995年 / 5卷 / 06期

关键词：

D O I：

10.1016/0959-437X(95)80013-U

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Chromosome painting has become a routine tool in comparative cytogenetics. The utility of interspecies chromosome painting has been demonstrated in taxa characterized by highly rearranged karyotypes such as in rodents and lesser apes. Chromosome painting also provides a new level of precision in comparative genome analysis for eliminating errors of confounding convergence with homology. Recent results hold promise that molecular cytogenetics will make a significant contribution to the understanding of the major features of genome evolution.

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页码：792 / 797

页数：6

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