EFFECTS OF A FERULA-SINAICA ROOT EXTRACT ON THE UTERINE SMOOTH-MUSCLE OF RAT AND GUINEA-PIG

被引：14

作者：

AQEL, MB ^{[1
]}

ALKHALIL, S ^{[1
]}

AFIFI, F ^{[1
]}

机构：

[1] UNIV JORDAN, FAC PHARM, AMMAN, JORDAN

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 1991年 / 31卷 / 03期

关键词：

D O I：

10.1016/0378-8741(91)90014-5

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The effects of an ethanolic extract of Ferula sinaica roots on the uterine smooth muscles of rats and guinea pigs were tested in vitro using isolated uterine horns. The extract inhibited the spontaneous movements of rat and guinea pig uterine smooth muscle and also the contractions induced by oxytocin stimulation. These effects were concentration-dependent and reversible by tissue washing. These data suggest that this plant extract may have some antioxytocic potential.

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页码：291 / 297

页数：7

相关论文

共 11 条

[1] EFFECTS OF AN AQUEOUS EXTRACT OF FERULA-OVINA ON RABBIT AND GUINEA-PIG SMOOTH-MUSCLE [J].

ALKHALIL, S ;

AQEL, M ;

AFIFI, F ;

ALEISAWI, D .

JOURNAL OF ETHNOPHARMACOLOGY, 1990, 30 (01) :35-42

[2] RELAXANT EFFECTS OF FERULA-SINAICA ROOT EXTRACT ON RABBIT AND GUINEA-PIG SMOOTH-MUSCLE [J].

AQEL, MB ;

ALKHALIL, S ;

AFIFI, F ;

ALEISAWI, D .

JOURNAL OF ETHNOPHARMACOLOGY, 1991, 31 (03) :373-381

[3]

BABAEV NF, 1983, AZERBAIDZHANSKII MED, V60, P67

[4] MECHANISMS OF ACTION OF TRANSMITTERS AND OTHER SUBSTANCES ON SMOOTH-MUSCLE [J].

BOLTON, TB .

PHYSIOLOGICAL REVIEWS, 1979, 59 (03) :606-718

[5]

French D., 1971, CHEM BIOL UMBELLIFER, P285

[6] ARDISIACRISPIN-A AND ARDISIACRISPIN-B, 2 UTERO-CONTRACTING SAPONINS FROM ARDISIA-CRISPA [J].

JANSAKUL, C ;

BAUMANN, H ;

KENNE, L ;

SAMUELSSON, G .

PLANTA MEDICA, 1987, (05) :405-409

[7] A UTERINE RELAXANT COMPOUND FROM ZINGIBER-CASSUMUNAR [J].

KANJANAPOTHI, D ;

SOPARAT, P ;

PANTHONG, A ;

TUNTIWACHWUTTIKUL, P ;

REUTRAKUL, V .

PLANTA MEDICA, 1987, (04) :329-332

[8]

MANSUROV MM, 1984, DOKL AKAD NAUK SSSR, V9, P50

[9] THE ZOAPATLE .15. ACTIVITY OF 16-ALPHA-HYDROXY-ENT-KAURAN-19-OIC ACID ISOLATED FROM MONTANOA-HIBISCIFOLIA, AND ITS METHYL-ESTER ON RAT AND GUINEA-PIG UTERUS [J].

PONCEMONTER, H ;

CAMPOSLARA, G ;

PEDRON, N ;

DELATORRE, L ;

VILLANUEVA, T ;

GALLEGOS, A ;

DEVIVAR, AR ;

AZPEITIA, E ;

PEREZ, A .

JOURNAL OF ETHNOPHARMACOLOGY, 1988, 24 (2-3) :127-134

[10]

SINITSIN GS, 1982, VESTENZHANSKII AKADE, V4, P39