LATERAL DIFFUSION OF MEMBRANE-LIPIDS AND PROTEINS IS INCREASED SPECIFICALLY IN NEURITES OF DIFFERENTIATING NEURO-BLASTOMA CELLS

被引：49

作者：

DELAAT, SW

VANDERSAAG, PT

ELSON, EL

SCHLESSINGER, J

机构：

[1] CORNELL UNIV,DEPT CHEM,ITHACA,NY 14853

[2] WEIZMANN INST SCI,DEPT CHEM IMMUNOL,REHOVOT 76100,ISRAEL

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1979年 / 558卷 / 02期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

(Neuroblastoma cell); Differentiation; Fluidity; Lateral diffusion; Membrane Lipid; Membrane protein;

D O I：

10.1016/0005-2736(79)90064-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Lateral diffusion of membrane lipids and proteins was determined in differentiating C1300 mouse neuroblastoma cells by fluorescence photobleaching recovery measurements. It is demonstrated that upon differentiation the lateral diffusion of membrane lipids and proteins is increased specifically in the extending neurites. This indicates the appearance of a topographical heterogeneity in the cell membrane, whereby more fluid domains become located in the membrane of the neurites. © 1979.

引用

页码：247 / 250

页数：4

共 13 条

[1] MOBILITY MEASUREMENT BY ANALYSIS OF FLUORESCENCE PHOTOBLEACHING RECOVERY KINETICS [J].