NITRIC-OXIDE AS A SIGNAL IN BLOOD-VESSELS

被引：264

作者：

KNOWLES, RG

MONCADA, S

机构：

[1] The Wellcome Research Laboratories, Beckenham, Kent BR3 3BS, Langley Court

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1992年 / 17卷 / 10期

关键词：

D O I：

10.1016/0968-0004(92)90008-W

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In the five years since the discovery that nitric oxide is produced as a signal in blood vessels, a great deal has been discovered about the processes involved. This article reviews current knowledge about the vascular cell synthesis, effects and subsequent destruction of this messenger molecule.

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页码：399 / 402

页数：4

相关论文

共 31 条

[11] ENDOTHELIAL NITRIC-OXIDE SYNTHASE - MOLECULAR-CLONING AND CHARACTERIZATION OF A DISTINCT CONSTITUTIVE ENZYME ISOFORM [J].

LAMAS, S ;

MARSDEN, PA ;

LI, GK ;

TEMPST, P ;

MICHEL, T .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (14) :6348-6352

[12]

LEONE AM, 1991, J BIOL CHEM, V266, P23790

[13] BRAIN NITRIC-OXIDE SYNTHASE IS A BIOPTERIN-CONTAINING AND FLAVIN-CONTAINING MULTIFUNCTIONAL OXIDOREDUCTASE [J].

MAYER, B ;

JOHN, M ;

HEINZEL, B ;

WERNER, ER ;

WACHTER, H ;

SCHULTZ, G ;

BOHME, E .

FEBS LETTERS, 1991, 288 (1-2) :187-191

[14]

MONCADA S, 1991, PHARMACOL REV, V43, P109

[15]

OCONNOR KJ, 1991, BIOCHIM BIOPHYS ACTA, V1097, P227, DOI 10.1016/0925-4439(91)90040-G

[16] THE ROLE OF NITRIC-OXIDE IN ENDOTHELIAL-CELL DAMAGE AND ITS INHIBITION BY GLUCOCORTICOIDS [J].

PALMER, RMJ ;

BRIDGE, L ;

FOXWELL, NA ;

MONCADA, S .

BRITISH JOURNAL OF PHARMACOLOGY, 1992, 105 (01) :11-12

[17] NITRIC-OXIDE RELEASE ACCOUNTS FOR THE BIOLOGICAL-ACTIVITY OF ENDOTHELIUM-DERIVED RELAXING FACTOR [J].

PALMER, RMJ ;

FERRIGE, AG ;

MONCADA, S .

NATURE, 1987, 327 (6122) :524-526

[18]

PULLOCK JS, 1991, P NATL ACAD SCI USA, V88, P10480

[19]

RAIFER J, 1992, NEW ENGL J MED, V326, P90

[20] IMMEDIATE RELEASE OF A NITRIC OXIDE-LIKE FACTOR FROM BOVINE AORTIC ENDOTHELIAL-CELLS BY ESCHERICHIA-COLI LIPOPOLYSACCHARIDE [J].

SALVEMINI, D ;

KORBUT, R ;

ANGGARD, E ;

VANE, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (07) :2593-2597

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