MOLECULAR-COMPLEXES OF CYCLODEXTRINS - APPLICATION OF ION-SPRAY MASS-SPECTROMETRY TO THE STUDY OF COMPLEXES WITH SELECTED NITRAMINES

被引：11

作者：

BAKHTIAR, R

BULUSU, S

机构：

[1] USA,CTR ARMAMENTS RES DEV & ENGN,DIV ENERGET MAT,PICATINNY ARSENAL,NJ 07806

[2] MERCK RES LABS,DEPT DRUG METAB 1,RAHWAY,NJ 07065

来源：

RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 1995年 / 9卷 / 14期

关键词：

D O I：

10.1002/rcm.1290091413

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Complex formation of the important nitramines, RDX, HMX and TNAZ with alpha-, beta-, and gamma-cyclodextrins (CDs) was studied using ion-spray mass spectrometry (IS-MS). Complexations between beta-CD/TNAZ, beta-CD/RDX, gamma-CD/RDX, and gamma-CD/HMX were detected in the gas phase by this technique. Control experiments using alpha-CD and TNAZ did not lead to a detectable molecular association, which is in accord with the previously reported NMR data. In addition, none of the nitramines showed any complex formation with the non-cyclic sugar, maltohexose. The IS-MS results are in agreement with the previously reported conclusions from proton nuclear magnetic resonance spin-lattice relaxation time measurements.

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页码：1391 / 1394

页数：4

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