RISK OF DEATH FROM CANCER AND ISCHEMIC-HEART-DISEASE IN MEAT AND NONMEAT EATERS

被引:122
作者
THOROGOOD, M
MANN, J
APPLEBY, P
MCPHERSON, K
机构
[1] UNIV OTAGO, DEPT HUMAN NUTR, DUNEDIN, NEW ZEALAND
[2] UNIV LONDON LONDON SCH HYG & TROP MED, DEPT PUBL HLTH & POLICY, LONDON WC1E 7HT, ENGLAND
[3] UNIV OXFORD, DEPT PUBL HLTH & PRIMARY CARE, OXFORD OX2 6HE, ENGLAND
来源
BMJ-BRITISH MEDICAL JOURNAL | 1994年 / 308卷 / 6945期
关键词
D O I
10.1136/bmj.308.6945.1667
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective-To investigate the consequences of a vegetarian diet by examining the 12 year mortality of non-meat eaters and meat eating controls. Design-Prospective observational study in which members of the non-meat eating cohort were asked to nominate friends or relatives as controls. Setting-United Kingdom. Subjects-6115 non-meat eaters identified through the Vegetarian Society of the United Kingdom and the news media (mean (SD) age 38.7 (16.8) years) and 5015 controls who were meat eaters (39.3 (15.4) years). Main outcome measures-Standardised mortality ratios for cancer, ischaemic heart disease, and total mortality in the two cohorts and death rate ratio in the non-meat eaters compared with meat eaters after adjustment for potentially confounding variables. Results-Standardised mortality ratios (taking the value among the general population as 100) for ischaemic heart disease were 51 (95% confidence interval 38 to 66) for meat eaters and 28 (20 to 38) for non-meat eaters (P <0.01). Values for all cancers were 80 (64 to 98) and 50 (39 to 62) for meat eaters and non-meat eaters respectively. After adjustment for the effects of smoking, body mass index, and socioeconomic status death rate ratios in non-meat eaters compared with meat eaters were 0.72 (0.47 to 1.10) for ischaemic heart disease and 0.61 (0.44 to 0.84) for all cancers. Conclusions-The reduced mortality from cancer among those not eating meat is not explained by lifestyle related risk factors, which have a low prevalence among vegetarians. No firm conclusion can be made about deaths from ischaemic heart disease. These data do not justify advice to exclude meat from the diet since there are several attributes of a vegetarian diet apart from not eating meat which might reduce the risk.
引用
收藏
页码:1667 / 1670
页数:4
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