REDUCTIVE RING-OPENING OF OXABICYCLIC COMPOUNDS WITH DIISOBUTYLALUMINUM HYDRIDE - APPLICATION TO THE SYNTHESIS OF THE C-17-C-23 SUBUNIT OF IONOMYCIN

被引：42

作者：

LAUTENS, M

CHIU, P

COLUCCI, JT

机构：

[1] Department of Chemistry, University of Toronto, Toronto, Ontario

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1993年 / 32卷 / 02期

关键词：

D O I：

10.1002/anie.199302811

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Not acetate aldol reactions but the reductive ring-opening of oxabicyclic compounds with diisobutylaluminum hydride (DIBAH) paved the way to the synnthesis of important precursors to natural products. The reactions summarized in Equation (a) show the potential of the method with simple examples. TB-DMS = tBuMe2Si.

引用

页码：281 / 283

页数：3

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