EFFECT OF HYDROCORTISONE ON SUPEROXIDE PRODUCTION BY LEUKOCYTES

被引：34

作者：

FUENFER, MM ^{[1
]}

CARR, EA ^{[1
]}

POLK, HC ^{[1
]}

机构：

[1] UNIV LOUISVILLE,HLTH SCI CTR,SCH MED,DEPT PHARMACOL,LOUISVILLE,KY 40232

来源：

JOURNAL OF SURGICAL RESEARCH | 1979年 / 27卷 / 01期

关键词：

D O I：

10.1016/0022-4804(79)90106-9

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Corticosteroids have been shown to significantly depress intracellular bactericidal pathways. Formation of superoxide anion (O2-) is thought to be an important intermediary in this process. We have demonstrated that actively phagocytizing PMNs generate significantly diminished levels of O2- in the presence of hydrocortisone sodium succinate. © 1979.

引用

页码：29 / 35

页数：7

共 28 条

[21] SINGLET OXYGEN - UNIQUE MICROBICIDAL AGENT IN CELLS
MAUGH, TH
[J]. SCIENCE, 1973, 182 (4107) : 44 - 45
[22] FAILURE OF NITRO BLUE TETRAZOLIUM REDUCTION IN PHAGOCYTIC VACUOLES OF LEUKOCYTES IN CHRONIC GRANULOMATOUS DISEASE
NATHAN, DG
BAEHNER, RL
WEAVER, DK
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1969, 48 (10) : 1895 - &
[23] CORTICOSTEROIDS, SERUM, AND PHAGOCYTOSIS - IN-VITRO AND IN-VIVO STUDIES
OLDS, JW
REED, WP
EBERLE, B
KISCH, AL
[J]. INFECTION AND IMMUNITY, 1974, 9 (03) : 524 - 529
[24] PARK BH, 1968, LANCET, V2, P532
[25] PHYSIOLOGICAL DISPOSITION AND METABOLIC FATE OF HYDROCORTISONE IN MAN
PETERSON, RE
WYNGAARDEN, JB
GUERRA, SL
BRODIE, BB
BUNIM, JJ
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1955, 34 (12) : 1779 - 1794
[26] SBARRA AJ, 1972, J RETICULOENDOTH SOC, V12, P109
[27] EFFECT OF CORTICOSTEROIDS ON HUMAN MONOCYTE IGG AND COMPLEMENT RECEPTORS
SCHREIBER, AD
PARSONS, J
MCDERMOTT, P
COOPER, RA
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1975, 56 (05) : 1189 - 1197
[28] INHIBITION OF THE ENZYMIC OXIDATION OF DPNH BY STEROID HORMONES
YIELDING, KL
TOMKINS, GM
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1959, 45 (12) : 1730 - 1739

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