NEW CHIRAL BIS(OXAZOLINYL)BIPYRIDINE LIGAND (BIPYMOX) - ENANTIOSELECTION IN THE ASYMMETRIC HYDROSILYLATION OF KETONES

被引：112

作者：

NISHIYAMA, H

YAMAGUCHI, S

PARK, SB

ITOH, K

机构：

[1] School of Materials Science, Toyohashi University of Technology, Toyohashi, 441, Tempaku-cho

来源：

TETRAHEDRON-ASYMMETRY | 1993年 / 4卷 / 01期

关键词：

D O I：

10.1016/S0957-4166(00)86024-3

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A homochiral chiral 6,6'-bis(oxazolinyl)-2,2'-bipyridine ligand, bipymox (1), and its rhodium complex were synthesized to examine the enantioselectivity in the asymmetric hydrosilylation of ketones in comparison to other chiral oxazoline ligands such as bis-(oxazolinyl)pyridine, pybox (2), and mono(oxazolinyl)pyridine, pymox (3). The bipymox-rhodium catalyst gave the (S)-absolute configuration of the product 1-phenylethanol (90 %ee) in the reduction of acetophenone with diphenylsilane the same as the pybox-rhodium system but opposite to the pymox-rhodium system. The reduction of 4-tert-butylcyclohexanone was also described.

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页码：143 / 150

页数：8

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