IN-VITRO ANTIBACTERIAL ACTIVITY OF SUCRALFATE

被引：10

作者：

BERGMANS, D

BONTEN, M

GAILLARD, C

VANTIEL, F

VANDERGEEST, S

STOBBERINGH, E

机构：

[1] UNIV LIMBURG HOSP,DEPT INTERNAL MED,6202 AZ MAASTRICHT,NETHERLANDS

[2] UNIV LIMBURG HOSP,DEPT MED MICROBIOL,6202 AZ MAASTRICHT,NETHERLANDS

来源：

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES | 1994年 / 13卷 / 07期

关键词：

D O I：

10.1007/BF01971318

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The effect of sucralfate (12.5 mg/ml) on the growth of Escherichia coli (ATCC 25922), Enterococcus faecalis (ATCC 29212) and two isolates of Pseudomonas aeruginosa (ATCC 27853 and a multi-resistant clinical isolate) was studied in vitro at pH values of 3.0, 4.5, 6.0 and 7.4. A bacteriostatic effect of sucralfate was demonstrated for Pseudomonas aeruginosa at a pH of 6.0 and 7.4 and for Escherichia coli and Enterococcus faecalis at a pH of 6.0. The bacteriostatic effect was most pronounced at high pH values. Sucralfate had no bactericidal effect on the bacteria tested at the concentration used.

引用

页码：615 / 620

页数：6

共 11 条

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