TRISOMY-11 AND OTHER NONRANDOM TRISOMIES IN CONGENITAL FIBROSARCOMA

被引：16

作者：

BERNSTEIN, R

ZELTZER, PM

LIN, F

CARPENTER, PM

机构：

[1] UNIV CALIF IRVINE,COLL MED,DIV HUMAN GENET,ORANGE,CA 92613

[2] UNIV CALIF IRVINE,COLL MED,DIV HEMATOL ONCOL,ORANGE,CA 92613

[3] UNIV CALIF IRVINE,COLL MED,DEPT PEDIAT,ORANGE,CA 92613

[4] UNIV CALIF IRVINE,COLL MED,DEPT PATHOL,ORANGE,CA 92613

来源：

CANCER GENETICS AND CYTOGENETICS | 1994年 / 78卷 / 01期

关键词：

D O I：

10.1016/0165-4608(94)90051-5

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Chromosome studies in a 7-week-old female infant with an intraabdominal malignant fibrosarcoma showed a hyperdiploid karyotype of 50,XX, +der(6)del(6)(p23)add(6)(q11), +8, +10, +11,add(12)(p13). Trisomy 11 appears to be a nonrandom primary cytogenetic abnormality in the congenital or infantile form of this mesenchymal tumor and is also a nonrandom gain in congenital mesoblastic nephroma. A possible developmental link between these two mesenchymal tumors, mediated by a gene or genes on chromosome 11 is postulated.

引用

页码：82 / 86

页数：5

共 22 条

[1] CYTOGENETIC ANALYSIS OF A CONGENITAL FIBROSARCOMA [J].