SYNTHESIS OF NATURAL LENTIGINOSINE EMPLOYING A CYCLIC IMIDE WITH C-2-SYMMETRY DERIVED FROM L-TARTARIC ACID

被引：61

作者：

YODA, H

KITAYAMA, H

KATAGIRI, T

TAKABE, K

机构：

[1] Department of Applied Chemistry, Faculty of Engineering, Shizuoka University, Hamamatsu

来源：

TETRAHEDRON-ASYMMETRY | 1993年 / 4卷 / 07期

关键词：

D O I：

10.1016/S0957-4166(00)80340-7

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The first efficient and simple process is described for the synthesis of a new (1S, 2S, 8aS)-1,2-dihydroxyindolizidine alkaloid, lentiginosine. The synthetic strategy is based on asymmetric deoxygenation of the quarternary alpha-hydroxy lactam prepared from a C2-symmetrical imide derived from L-tartaric acid.

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页码：1455 / 1456

页数：2

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