DIFFERENTIAL DIAGNOSTIC-VALUE OF PLASMA-CELLS IN BRONCHOALVEOLAR LAVAGE FLUID

被引：26

作者：

DRENT, M

VANVELZENBLAD, H

DIAMANT, M

WAGENAAR, SS

DONCKERWOLCKEBOGAERT, M

VANDENBOSCH, JMM

机构：

[1] ST ANTONIUS HOSP, DEPT PULM DIS, KOEKOEKSLAAN 1, 3435 CM NIEUWEGEIN, NETHERLANDS

[2] ST ANTONIUS HOSP, DEPT IMMUNOL, NIEUWEGEIN, NETHERLANDS

[3] ST ANTONIUS HOSP, DEPT PATHOL, NIEUWEGEIN, NETHERLANDS

来源：

CHEST | 1993年 / 103卷 / 06期

关键词：

D O I：

10.1378/chest.103.6.1720

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

The aim of this study was to investigate whether the demonstration of plasma cells (PC), which are normally absent in bronchoalveolar lavage (BAL) fluid, facilitates differentiation among pulmonary disorders. Initial BAL fluid samples of 1,260 patients were analyzed. In 83 of these, PC were found. Of these 83, 47 were obtained from individuals suffering from extrinsic allergic alveolitis (EAA). The number of PC in BAL fluid from EAA patients was found related to the time between antigen exposure and BAL. Drug-induced pneumonitis appeared to be another disorder with a high percentage of cases with PC in the BAL fluid (35.7 percent). Therefore, we conclude that determination of PC in BAL fluid has differential diagnostic value in discriminating among interstitial lung diseases of various origins. However, the exact role of BAL fluid and PC and the link to clinical manifestations of these diseases needs further investigation.

引用

页码：1720 / 1724

页数：5

共 37 条

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