The effects of sulfur dioxide inhalation and antioxidant vitamins on red blood cell lipoperoxidation

被引：34

作者：

Etlik, O ^{[1
]}

Tomur, A ^{[1
]}

Kutman, MN ^{[1
]}

Yorukan, S ^{[1
]}

Duman, O ^{[1
]}

机构：

[1] HACETTEPE UNIV,FAC MED,DEPT PHYSIOL,TR-06100 ANKARA,TURKEY

来源：

ENVIRONMENTAL RESEARCH | 1995年 / 71卷 / 01期

关键词：

D O I：

10.1006/enrs.1995.1063

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

An attempt was made to determine whether sulfur dioxide (SO2) inhalation at 10 ppm, 1 hr daily, for 30 days induces oxidant stress and whether vitamin E (40 mg/kg) together with vitamin C (200 mg/kg), administered intraperitoneally once in every 3 days, can reduce the damage in red blood cell membranes of guinea pigs. Malonyldialdehyde (MDA) levels, osmotic fragility ratios, and methemoglobin and sulfhemoglobin values were significantly higher in the SO2-treated group compared with the control group (P < 0.05), and marked decreases in MDA levels and osmotic fragility ratios were determined in the group treated with SO2 + antioxidant vitamins (P < 0.05). (C) 1995 Academic Press, Inc.

引用

页码：25 / 28

页数：4