CONTROL OF CORONARY BLOOD-FLOW BY AUTACOIDS

被引：41

作者：

BASSENGE, E

机构：

[1] Institut für Angewandte Physiologie, Universität Freiburg, Freiburg, 79104

来源：

BASIC RESEARCH IN CARDIOLOGY | 1995年 / 90卷 / 02期

关键词：

FLOW DEPENDENT DILATION; CYCLOOXYGENASE; RENIN-ANGIOTENSIN SYSTEM; BRADYKININ; NO-SYNTHASE; TOLERANCE TO NO-DONORS;

D O I：

10.1007/BF00789443

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Coronary flow and thus myocardial perfusion is regulated by myogenic, metabolic, humoral and neuro-hormonal factors which closely interact with local autacoids released from the endothelial lining of the coronary bed. In a number of disease states an impaired synthesis and release of autacoids decisively limit the overall capacity of coronary regulation and adaptation of myocardial perfusion to increased metabolic demands. The important factors for these control mechanisms are analyzed and reviewed in this article.

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页码：125 / 141

页数：17

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