THERAPEUTIC EFFICACY OF LANOCONAZOLE, A NEW IMIDAZOLE ANTIMYCOTIC AGENT, FOR EXPERIMENTAL CUTANEOUS CANDIDIASIS IN GUINEA-PIGS

被引：30

作者：

NIWANO, Y

SEO, A

KANAI, K

HAMAGUCHI, H

UCHIDA, K

YAMAGUCHI, H

机构：

[1] NIHON NOHYAKU CO LTD,CHEM RES CTR,NISHIYODOGAWA KU,OSAKA 555,JAPAN

[2] TEIKYO UNIV,MED MYCOL RES CTR,HACHIOJI,TOKYO 19203,JAPAN

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1994年 / 38卷 / 09期

关键词：

D O I：

10.1128/AAC.38.9.2204

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The therapeutic efficacy of 1% cream and 1% solution of lanoconazole, a new imidazole antimycotic agent, in the model of cutaneous candidiasis in prednisolone-treated guinea pigs was evaluated in comparison with that of comparable formulations of bifonazole. Each preparation was topically applied once a day for 3 consecutive days, starting on the fifth day postinfection, and quantitative culture study was conducted on the ninth day postinfection. Both formulations of lanoconazole were much more highly effective in terms of eradication of fungi than the bifonazole formulations.

引用

页码：2204 / 2206

页数：3

共 8 条

[1] CHANGES IN THE ACTIVITY OF ANTIFUNGALS IN MIXED CULTURES OF BACTERIA AND YEASTS [J].