DETECTION OF VARIANT PH-POSITIVE CHRONIC MYELOGENOUS LEUKEMIA INVOLVING CHROMOSOMES-1, CHROMOSONE-9, AND CHROMOSONE-22 BY FLUORESCENCE INSITU HYBRIDIZATION

被引：24

作者：

SEONG, DC

LIU, P

SICILIANO, J

ZHAO, Y

CORK, A

HENSKE, E

WARBURTON, D

YU, MT

CHAMPLIN, R

TRUJILLO, JM

DEISSEROTH, A

SICILIANO, MJ

机构：

[1] UNIV TEXAS, M D ANDERSON CANC CTR, DEPT MOLECUL GENET, 1515 HOLCOMBE BLVD, HOUSTON, TX 77030 USA

[2] UNIV TEXAS, M D ANDERSON CANC CTR, DEPT HEMATOL, HOUSTON, TX 77030 USA

[3] UNIV TEXAS, M D ANDERSON CANC CTR, DEPT LAB MED, HOUSTON, TX 77030 USA

[4] BRIGHAM & WOMENS HOSP, DIV EXPTL MED, BOSTON, MA 02115 USA

[5] COLUMBIA UNIV, DEPT GENET & DEV, NEW YORK, NY 10027 USA

[6] COLUMBIA UNIV, DEPT PEDIAT, NEW YORK, NY 10027 USA

来源：

CANCER GENETICS AND CYTOGENETICS | 1993年 / 65卷 / 02期

关键词：

D O I：

10.1016/0165-4608(93)90214-7

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Probes made by inter-Alu-PCR from an interspecific somatic cell hybrid containing only the distal half of the 9q as its only human genomic content when used for fluorescence in situ hybridization (FISH) on the cells of a chronic myelogenous leukemia (CML) patient detected involvement of chromosome 9 in a complex translocation that was not observed by standard G-band cytogenetics.

引用

页码：100 / 103

页数：4

共 18 条

[1] C-ABL AND BCR ARE REARRANGED IN A PH1-NEGATIVE CML PATIENT [J].