FREE-ENERGY PROFILE FOR A HOST-ACCELERATED DIELS-ALDER REACTION - THE SOURCES OF EXO SELECTIVITY

被引：56

作者：

WALTER, CJ ^{[1
]}

SANDERS, JKM ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,CHEM LAB,CAMBRIDGE CTR MOLEC RECOGNIT,CAMBRIDGE CB2 1EW,ENGLAND

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1995年 / 34卷 / 02期

关键词：

DIELS-ALDER REACTIONS; ENZYME MODELS; HOST-GUEST CHEMISTRY; KINETICS; PORPHYRINOIDS;

D O I：

10.1002/anie.199502171

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Simultaneous reduction of the activation energy for the exo reaction and increase of that for the endo reaction explain how a cyclic porphyrin trimer that can bind diene 1 and dienophile 2 in its cavity increases the exo selectivity of a Diels–Alder reaction and accelerates it dramatically. (Figure Presented.) Copyright © 1995 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：217 / 219

页数：3

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