SC25152 - POTENT MINERALOCORTICOID ANTAGONIST WITH REDUCED AFFINITY FOR 5-ALPHA-DIHYDROTESTOSTERONE RECEPTOR OF HUMAN AND RAT PROSTATE

被引：14

作者：

CUTLER, GB ^{[1
]}

PITA, JC ^{[1
]}

RIFKA, SM ^{[1
]}

MENARD, RH ^{[1
]}

SAUER, MA ^{[1
]}

LORIAUX, DL ^{[1
]}

机构：

[1] NHLBI, CHEM PHARMACOL LAB, BETHESDA, MD 20014 USA

来源：

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | 1978年 / 47卷 / 01期

关键词：

D O I：

10.1210/jcem-47-1-171

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：171 / 175

页数：5

共 18 条

[1] GYNECOMASTIA AND SEMEN ABNORMALITIES INDUCED BY SPIRONOLACTONE IN NORMAL MEN [J].

CAMINOSTORRES, R ;

MA, L ;

SNYDER, PJ .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1977, 45 (02) :255-260

[2]

CAPLAN RM, 1967, J CLIN ENDOCR METAB, V27, P1348

[3] ANTIANDROGENIC EFFECT OF SPIROLACTONES - MECHANISM OF ACTION [J].

CORVOL, P ;

MICHAUD, A ;

MENARD, J ;

FREIFELD, M ;

MAHOUDEAU, J .

ENDOCRINOLOGY, 1975, 97 (01) :52-58

[4] MECHANISM OF ACTION OF STEROID-HORMONES [J].

EDELMAN, IS .

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1975, 6 (3-4) :147-159

[5] MOLECULAR MODIFICATIONS OF ANTI-ALDOSTERONE COMPOUNDS - EFFECTS ON AFFINITY OF SPIRONOLACTONES FOR RENAL ALDOSTERONE RECEPTORS [J].

FUNDER, JW ;

FELDMAN, D ;

HIGHLAND, E ;

EDELMAN, IS .

BIOCHEMICAL PHARMACOLOGY, 1974, 23 (10) :1493-1501

[6]

GELLER J, 1968, SURG GYNECOL OBSTETR, V127, P748

[7]

HOFMANN LM, 1977, J PHARMACOL EXP THER, V201, P762

[8] SPIRONOLACTONE AND ENDOCRINE DYSFUNCTION [J].

LORIAUX, DL ;

MENARD, R ;

TAYLOR, A ;

PITA, JC ;

SANTEN, R .

ANNALS OF INTERNAL MEDICINE, 1976, 85 (05) :630-636

[9] SPIRONOLACTONE AND TESTICULAR CYTOCHROME-P-450 - DECREASED TESTOSTERONE FORMATION IN SEVERAL SPECIES AND CHANGES IN HEPATIC DRUG-METABOLISM [J].

MENARD, RH ;

STRIPP, B ;

GILLETTE, JR .

ENDOCRINOLOGY, 1974, 94 (06) :1628-1636

[10]

PENTIKAINEN PJ, 1974, J INT MED RES, V2, P439

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