EXPRESSION OF THE ENVELOPE ANTIGEN-F1 OF YERSINIA-PESTIS IS MEDIATED BY THE PRODUCT OF CAF1M-GENE HAVING HOMOLOGY WITH THE CHAPERONE PROTEIN-PAPD OF ESCHERICHIA-COLI

被引：75

作者：

GALYOV, EE

KARLISHEV, AV

CHERNOVSKAYA, TV

DOLGIKH, DA

SMIRNOV, OY

VOLKOVOY, KI

ABRAMOV, VM

ZAVYALOV, VP

机构：

[1] LYUBUCHANY IMMUNOL INST,LYUBUCHANY 142380,USSR

[2] ALL UNION APPL MICROBIOL RES INST,OBOLENSK 142279,USSR

来源：

FEBS LETTERS | 1991年 / 286卷 / 1-2期

关键词：

CHAPERONE PROTEIN; NUCLEOTIDE SEQUENCE; ENVELOPE ANTIGEN EXPRESSION; YERSINIA-PESTIS;

D O I：

10.1016/0014-5793(91)80945-Y

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The effective synthesis of the envelope antigen F1 of Y. pestis in E. coli HB101 is mediated by the expression of the caf1M gene. This gene was sequenced, and the protein encoded was found to have a significant homology with the chaperone protein PapD of uropathogenic E. coli. The data presented allow one to suppose Caf1M and PapD proteins perform similar functions in the biogenesis of the Y. pestis capsule and E. coli P-pili, respectively.

引用

页码：79 / 82

页数：4

共 12 条

[1] NUCLEOTIDE-SEQUENCE OF THE YERSINIA-PESTIS GENE ENCODING F1 ANTIGEN AND THE PRIMARY STRUCTURE OF THE PROTEIN - PUTATIVE T-CELL AND B-CELL EPITOPES [J].