SYNTHESIS OF 2-SUBSTITUTED MYOINOSITOL 1,3,4,5-TETRAKIS(PHOSPHATE) AND 1,3,4,5,6-PENTAKIS(PHOSPHATE) ANALOGS

被引：31

作者：

OZAKI, S ^{[1
]}

KOGA, Y ^{[1
]}

LING, L ^{[1
]}

WATANABE, Y ^{[1
]}

KIMURA, Y ^{[1
]}

HIRATA, M ^{[1
]}

机构：

[1] KYUSHU UNIV, FAC DENT, DEPT BIOCHEM, FUKUOKA 812, JAPAN

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 1994年 / 67卷 / 04期

关键词：

D O I：

10.1246/bcsj.67.1058

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Some biologically interesting inositol poly(phosphate) derivatives, 2-O-(p-aminobenzoyl)-myo-inositol 1,3,4, 5-tetrakis(phosphate), 2-O-(4-aminocyclohexylcarbonyl)-myo-inositol 1,3,4,5-tetrakis(phosphate), myo-inositol 1,3,4,5,6-pentakis(phosphate), and its 2-substituted analogs, were synthesized. Inositol tetrakis(phosphate) and pentakis(phosphate) affinity columns were also prepared. The inositol 1,3,4,5-tetrakis(phosphate) affinity column was found to be effective in isolating the binding proteins from bovine cardiac membranes.

引用

页码：1058 / 1063

页数：6

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