Monitoring of lithium levels in human serum after therapy with lithium preparations by capillary isotachophoresis

被引：10

作者：

Valaskova, I

Balazova, J

Havranek, E

机构：

[1] Department of Pharmaceutical Analysis and Nuclear Pharmacy, Faculty of Pharmacy, Comenius University

来源：

JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS | 1995年 / 674卷 / 02期

关键词：

D O I：

10.1016/0378-4347(95)00326-6

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

An isotachophoretic method for the evaluation of the level of lithium salts in serum samples was optimized. Use of operating systems containing polyethylene glycol permitted the separation of cationically migrating components from Li (i.e., Na, K and Ca). The pretreatment of serum samples involves only appropriate dilution with demineralized water depending on the concentration of the major components such as sodium. The lithium levels were studied both in model samples and serum from patients treated with lithium preparations.

引用

页码：310 / 313

页数：4

共 15 条

[11] CBNM - DETERMINATION OF LI IN BCR REFERENCE MATERIALS RM-303 AND RM-304 LYOPHILIZED SERUM BY ISOTOPE-DILUTION MASS-SPECTROMETRY (IDMS) [J].