THE EFFECTS OF MAMMILLARY BODY LESIONS ON DELAYED MATCHING AND DELAYED NONMATCHING TO PLACE TASKS IN THE MICE

被引:32
作者
BERACOCHEA, DJ
JAFFARD, R
机构
[1] Laboratoire de Neurosciences Cognitives et Comportementales, URA CNRS 339, Université de Bordeaux I, 33405 Talence Cedex, Avenue des Facultés
关键词
AMNESIA; KORSAKOFF SYNDROME; MAMMILLARY BODY; MOUSE; RETRIEVAL PROCESS;
D O I
10.1016/0166-4328(94)00158-C
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
This study was designed to investigate the effects of different recognition procedures on memory performance in Balb/c mice. To this end, mice were submitted to spontaneous or contingently reinforced delayed non-matching (DNMTP) and delayed matching (DMTP) to place tasks in a T-maze. Results indicate that mammillary bodies (MM)-lesioned subjects are significantly impaired in the DNMTP tasks at the long (6 h) but not the short (5 min) delays; in contrast, they did not exhibit deficits in the DMTP task, whatever the delay considered. We stress the importance of task difficulty as a major factor explaining the different effects of the lesion in the two tasks.
引用
收藏
页码:45 / 52
页数:8
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