GLC DETERMINATION OF BUTYLATED HYDROXYANISOLE IN HUMAN-PLASMA AND URINE

被引：12

作者：

ELRASHIDY, R ^{[1
]}

NIAZI, S ^{[1
]}

机构：

[1] UNIV ILLINOIS,MED CTR,COLL PHARM,DEPT PHARM,CHICAGO,IL 60612

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1979年 / 68卷 / 01期

关键词：

Antioxidants—butylated hydroxyanisole; GLC analysis in plasma and urine; Butylated hydroxyanisole—GLC analysis in plasma and urine; GLC—analysis; butylated hydroxyanisole in plasma and urine;

D O I：

10.1002/jps.2600680134

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A highly sensitive and specific GLC method was developed for the analysis of butylated hydroxyanisole, a commonly used antioxidant. Concentrations below 100 ng/ml could be detected in human plasma and urine. Preliminary pharmacokinetic studies demonstrated that, upon administration of 100 mg po, butylated hydroxyanisole was quickly absorbed and removed from the plasma with a high degree of intersubject variability. Copyright © 1979 Wiley‐Liss, Inc., A Wiley Company

引用

页码：103 / 104

页数：2

共 11 条

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