OUTBREAK OF SHIGELLA-SONNEI INFECTION TRACED TO IMPORTED ICEBERG LETTUCE

被引:126
作者
KAPPERUD, G
RORVIK, LM
HASSELTVEDT, V
HOIBY, EA
IVERSEN, BG
STAVELAND, K
JOHNSEN, G
LEITAO, J
HERIKSTAD, H
ANDERSSON, Y
LANGELAND, G
GONDROSEN, B
LASSEN, J
机构
[1] NORWEGIAN COLL VET MED,N-0033 OSLO,NORWAY
[2] FOOD INSPECT SERV MIDT ROGALAND,N-4033 FORUS,NORWAY
[3] NORSKE SHELL,N-4056 TANANGER,NORWAY
[4] NORWEGIAN FOOD CONTROL AUTHOR,N-0034 OSLO,NORWAY
[5] SWEDISH INST INFECT DIS CONTROL,S-10521 STOCKHOLM,SWEDEN
关键词
D O I
10.1128/JCM.33.3.609-614.1995
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In the period from May through June 1994, an increase in the number of domestic Lases of Shigella sonnei infection was detected in several European countries, including Norway, Sweden, and the United Kingdom. In all three countries epidemiological evidence incriminated imported iceberg lettuce of Spanish origin as the vehicle of transmission. The outbreaks shared a number of common features: a predominance of adults among the case patients, the presence of double infections with other enteropathogens, and the finding of two dominant phage types among the bacterial isolates. In Norway 110 culture-confirmed cases of infection were recorded; more than two-thirds (73%) mere adults aged 30 to 60 years. A nationwide case-control study comprising 47 case patients and 155 matched control individuals showed that the consumption of imported iceberg lettuce was independently associated viith an increased risk of shigellosis. Epidemiological investigation of a local outbreak incriminated iceberg lettuce from Spain, consumed from a salad bar, as the source. The presence of shigellae in the suspected food source could not be documented retrospectively. However, high numbers of fecal coliforms were detected in iceberg lettuce from patients' homes. Three lettuce specimens yielded salmonellae. The imported iceberg lettuce harbored Escherichia coli strains showing resistance to several antimicrobial agents, including ampicillin, ciprofloxacin, gentamicin, and trimethoprim-sulfamethoxazole. During the outbreak it is likely that thousands of Norwegians and an unknown number of consumers in other countries were exposed to coliforms containing antibiotic resistance genes.
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页码:609 / 614
页数:6
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