SYNTHETIC STUDIES TOWARDS THE SQUALESTATINS AND ZARAGOZIC ACIDS

被引：39

作者：

MCVINISH, LM ^{[1
]}

RIZZACASA, MA ^{[1
]}

机构：

[1] UNIV MELBOURNE,SCH CHEM,PARKVILLE,VIC 3052,AUSTRALIA

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 06期

关键词：

D O I：

10.1016/S0040-4039(00)76001-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A synthesis of a model core system (18) of the squalestatins and zaragozic acids has been achieved from D-mannose. The key steps involve an Ireland-Claisen rearrangement of the allyl ester 5 and a stereoselective epoxidation of the furanoid glycal 12 with 2,2-dimethyldioxirane.

引用

页码：923 / 926

页数：4

共 15 条

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