CHONDROITIN SULFATE AS A REGULATOR OF NEURONAL PATTERNING IN THE RETINA

被引：386

作者：

BRITTIS, PA

CANNING, DR

SILVER, J

机构：

[1] Department of Neuroscienccs, Case Western Reserve University, Cleveland

来源：

SCIENCE | 1992年 / 255卷 / 5045期

关键词：

D O I：

10.1126/science.1738848

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Highly sulfated proteoglycans are correlated with axon boundaries in the developing central nervous system which suggests that these molecules affect neural pattern formation. In the developing mammalian retina, gradual regression of chondroitin sulfate may help control the onset of ganglion cell differentiation and initial direction of their axons. Changes induced by the removal of chondroitin sulfate from intact retinas in culture confirm the function of chondroitin sulfate in retinal histogenesis.

引用

页码：733 / 736

页数：4

共 21 条

[11] GLYCOSAMINOGLYCANS OF BRAIN DURING DEVELOPMENT
MARGOLIS, RU
MARGOLIS, RK
CHANG, LB
PRETI, C
[J]. BIOCHEMISTRY, 1975, 14 (01) : 85 - 88
[12] PROTEOGLYCANS SYNTHESIZED BY EMBRYONIC CHICKEN RETINA IN CULTURE - COMPOSITION AND COMPARTMENTALIZATION
MORRIS, JE
YANAGISHITA, M
HASCALL, VC
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1987, 258 (01) : 206 - 218
[13] NEWGREEN DF, 1986, CELL TISSUE RES, V244, P299
[14] PROTEOGLYCANS AS MODULATORS OF GROWTH-FACTOR ACTIVITIES
RUOSLAHTI, E
YAMAGUCHI, Y
[J]. CELL, 1991, 64 (05) : 867 - 869
[15] Sidman R., 1961, STRUCTURE EYE, P487
[16] STUDIES ON THE DEVELOPMENT OF THE EYE CUP AND OPTIC-NERVE IN NORMAL MICE AND IN MUTANTS WITH CONGENITAL OPTIC-NERVE APLASIA
SILVER, J
ROBB, RM
[J]. DEVELOPMENTAL BIOLOGY, 1979, 68 (01) : 175 - 190
[17] GUIDANCE OF OPTIC AXONS INVIVO BY A PREFORMED ADHESIVE PATHWAY ON NEUROEPITHELIAL ENDFEET
SILVER, J
RUTISHAUSER, U
[J]. DEVELOPMENTAL BIOLOGY, 1984, 106 (02) : 485 - 499
[18] SULFATED PROTEOGLYCANS IN ASTROGLIAL BARRIERS INHIBIT NEURITE OUTGROWTH INVITRO
SNOW, DM
LEMMON, V
CARRINO, DA
CAPLAN, AI
SILVER, J
[J]. EXPERIMENTAL NEUROLOGY, 1990, 109 (01) : 111 - 130
[19] PROTEOGLYCAN BIOSYNTHESIS BY CHICK-EMBRYO RETINA GLIAL-LIKE CELLS
THRELKELD, A
ADLER, R
HEWITT, AT
[J]. DEVELOPMENTAL BIOLOGY, 1989, 132 (02) : 559 - 568
[20] FORMATION OF THE RETINAL GANGLION-CELL AND OPTIC FIBER LAYERS
WATANABE, M
RUTISHAUSER, U
SILVER, J
[J]. JOURNAL OF NEUROBIOLOGY, 1991, 22 (01): : 85 - 96

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