REACTIONS OF POLYFLUORO-2-ALKYNOIC ACIDS WITH BIFUNCTIONAL HETERONUCLEOPHILES LEADING TO POLYFLUOROALKYLATED HETEROCYCLES

被引：17

作者：

YAMANAKA, H

TAMURA, K

FUNABIKI, K

FUKUNISHI, K

ISHIHARA, T

机构：

[1] Department of Chemistry and Materials Technology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto

来源：

JOURNAL OF FLUORINE CHEMISTRY | 1992年 / 57卷 / 1-3期

关键词：

D O I：

10.1016/S0022-1139(00)82830-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Polyfluoro-2-alkynoic acids, R(f)-C=C-COOH (R(f) = HCF2, CF3, H(CF2)3), readily undergo tandem intermolecular-intramolecular Michael addition with bifunctional hetero nucleophiles, HX(CH2)nYH (X, Y = S, O; n = 2, 3), to give 2-polyfluoroalkylated 1,3-diheterocyclic compounds in good to excellent yields.

引用

页码：177 / 190

页数：14

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