NUCLEAR MAGNETIC-RESONANCE STUDY OF THE SOLUTION CONFORMATION OF ADENINE MONO-NUCLEOTIDES USING THE LANTHANIDE PROBE METHOD

被引：15

作者：

GERALDES, CFGC ^{[1
]}

机构：

[1] INORGAN CHEM LAB,OXFORD OX1 3QR,ENGLAND

来源：

JOURNAL OF MAGNETIC RESONANCE | 1979年 / 36卷 / 01期

关键词：

D O I：

10.1016/0022-2364(79)90218-X

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The use of lanthanide ions as NMR shift and relaxation probes has enabled the determination of the conformations of adenosine 2′-monophosphate and adenosine 3′-monophosphate in aqueous solution. These nucleotides are much more flexible than the corresponding 5′-mononucleotide. The interpretation of the lanthanide data, based on mixing different conformations in fast exchange within the NMR time scale, agrees well with conformational evidence for the metal-free systems, obtained from independent NMR methods. © 1979.

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页码：89 / 98

页数：10

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