HIGHLY EFFECTIVE SURFACTANTS WITH LOW HEMOLYTIC-ACTIVITY

被引：44

作者：

RIESS, JG ^{[1
]}

PACE, S ^{[1
]}

ZARIF, L ^{[1
]}

机构：

[1] UNIV NICE,CNRS,UNITE CHIM MOLEC,F-06034 NICE,FRANCE

来源：

ADVANCED MATERIALS | 1991年 / 3卷 / 05期

关键词：

D O I：

10.1002/adma.19910030507

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Communication: Fluorochemicals show potential as highly surface-active but non-hemolyzing surfactants, an important combination of properties for biomedical applications such as blood substitutes and contrast agents. Hydrocarbon-based surfactants suffer from the disadvantage that as the length of the hydrocarbon chain (and therefore surface activity) increases, cell-destruction (hemolysis) also increases. The fluorinated surfactants, however, exhibit the opposite effect, an increase in chain length and surface activity leading to reduced hemolysis.

引用

页码：249 / 251

页数：3