ARCHAEBACTERIAL LIPIDS - SURFACE PRESSURE-SURFACE AREA ISOTHERMS OF 1,1'-(1,32-DOTRIACONTANEDIYL)BIS[2-[(3RS,7R,11R)-3,7,11,15-TETRAMETHYL-HEXADECYL]-SN-GLYCERO-3-PHOSPHOCHOLINE]

被引：20

作者：

YAMAUCHI, K ^{[1
]}

YAMADA, K ^{[1
]}

KINOSHITA, M ^{[1
]}

KAMIKAWA, T ^{[1
]}

机构：

[1] KINKI UNIV, FAC SCI & TECHNOL, DEPT CHEM, OSAKA, OSAKA 577, JAPAN

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 1991年 / 64卷 / 07期

关键词：

D O I：

10.1246/bcsj.64.2088

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

1,1'-(1,32-Dotriacontanediyl)bis[2-[(3RS,7R,11R)-3,7,11,15-tetramethylhexadecyl]-sn-glycero-3-phosphocholine] (the tetramethylhexadecyl group = phytanyl) was synthesized conveniently by reactions involving etherification of 1,1'-(1,32-dotriacontanediyl)bis(3-benzyl-sn-glycerol) (1) with (7R,11R)-3,7,11,15-tetramethyl-2-hexadecenyl bromide and hydrogenation of the resulting unsaturated ether with p-tolylsulfonylhydrazine; a total yield from 1,7-10%. Unlike usual monopolar double-chain-amphiphiles, the bipolar lipid bent into a U-form in a water-air interface to produce the Langmuir membrane, exhibiting peculiar surface pressure-surface area isotherms.

引用

页码：2088 / 2090

页数：3

共 7 条

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