THE PAGETOID VARIANT OF UROTHELIAL CARCINOMA IN-SITU

被引:31
作者
OROZCO, RE
VANDERZWAAG, R
MURPHY, WM
机构
[1] BAPTIST MEM HOSP,DEPT DATA MANAGEMENT,MEMPHIS,TN 38146
[2] UNIV TENNESSEE CTR HLTH SCI,DEPT PATHOL,MEMPHIS,TN 38163
关键词
PAGETOID CARCINOMA IN-SITU; UROTHELIAL CARCINOMA IN-SITU; PAGETOID VARIANT;
D O I
10.1016/0046-8177(93)90216-4
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
The frequency, distribution, and clinical significance of pagetoid changes in urothelial carcinoma in situ (CIS) were studied in over 600 tissue slides from 102 patients followed for a mean period of over 4 years. Results indicate that pagetoid changes are unusual, randomly distributed, and never widespread. These changes occur in a histologic setting of CIS and apparently never appear as the initial lesion, even in cases in which CIS is the primary or only neoplasm. Patients manifesting pagetoid CIS had essentially the same progression and survival rates as patients without pagetoid changes. Our data suggest that this histologic pattern represents a peculiar reaction to injury confined to small areas of urothelium in susceptible hosts. © 1993.
引用
收藏
页码:1199 / 1202
页数:4
相关论文
共 13 条
  • [11] PAGETS-DISEASE OF THE URETHRAL MEATUS FOLLOWING TRANSITIONAL CELL-CARCINOMA OF THE BLADDER
    TOMASZEWSKI, JE
    KORAT, OC
    LIVOLSI, VA
    CONNOR, AM
    WEIN, A
    [J]. JOURNAL OF UROLOGY, 1986, 135 (02) : 368 - 370
  • [12] PAGETOID LESIONS ASSOCIATED WITH CARCINOMA OF THE BLADDER
    TURNER, AG
    [J]. JOURNAL OF UROLOGY, 1980, 123 (01) : 124 - 126
  • [13] YAMADA T, 1975, JPN J CLIN ONCOL, V5, P77