THE SPECIFICITY OF OMEPRAZOLE AS AN (H+ + K+)-ATPASE INHIBITOR DEPENDS UPON THE MEANS OF ITS ACTIVATION

被引：61

作者：

KEELING, DJ

FALLOWFIELD, C

UNDERWOOD, AH

机构：

来源：

BIOCHEMICAL PHARMACOLOGY | 1987年 / 36卷 / 03期

关键词：

D O I：

10.1016/0006-2952(87)90291-7

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

收藏

页码：339 / 344

页数：6

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共 10 条

[1] THE PREPARATION OF C-14,S-35 AND C-13 LABELED FORMS OF OMEPRAZOLE
CROWE, AM
IFE, RJ
MITCHELL, MB
SAUNDERS, D
[J]. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 1986, 23 (01) : 21 - 33
[2] SUBSTITUTED BENZIMIDAZOLES INHIBIT GASTRIC-ACID SECRETION BY BLOCKING (H++K+)ATPASE
FELLENIUS, E
BERGLINDH, T
SACHS, G
OLBE, L
ELANDER, B
SJOSTRAND, SE
WALLMARK, B
[J]. NATURE, 1981, 290 (5802) : 159 - 161
[3] ACID ACTIVATION OF (H+-K+)-ATPASE INHIBITING 2-(2-PYRIDYLMETHYL-SULPHINYL)BENZIMIDAZOLES - ISOLATION AND CHARACTERIZATION OF THE THIOPHILIC ACTIVE PRINCIPLE AND ITS REACTIONS
FIGALA, V
KLEMM, K
KOHL, B
KRUGER, U
RAINER, G
SCHAEFER, H
SENNBILFINGER, J
STURM, E
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1986, (02) : 125 - 127
[4] INHIBITION OF (H+ + K+)-ATPASE AND H+ ACCUMULATION IN HOG GASTRIC MEMBRANES BY TRIFLUOPERAZINE, VERAPAMIL AND 8-(N,N-DIETHYLAMINO)OCTYL-3,4,5-TRIMETHOXYBENZOATE
IM, WB
BLAKEMAN, DP
MENDLEIN, J
SACHS, G
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1984, 770 (01) : 65 - 72
[5] STUDIES ON THE MECHANISM OF ACTION OF OMEPRAZOLE
KEELING, DJ
FALLOWFIELD, C
MILLINER, KJ
TINGLEY, SK
IFE, RJ
UNDERWOOD, AH
[J]. BIOCHEMICAL PHARMACOLOGY, 1985, 34 (16) : 2967 - 2973
[6] THE MECHANISM FOR INHIBITION OF GASTRIC (H++K+)-ATPASE BY OMEPRAZOLE
LORENTZON, P
EKLUNDH, B
BRANDSTROM, A
WALLMARK, B
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1985, 817 (01) : 25 - 32
[7] LOWRY OH, 1951, J BIOL CHEM, V193, P265
[8] EVIDENCE FOR ACID-INDUCED TRANSFORMATION OF OMEPRAZOLE INTO AN ACTIVE INHIBITOR OF (H+ + K+)-ATPASE WITHIN THE PARIETAL-CELL
WALLMARK, B
BRANDSTROM, A
LARSSON, H
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1984, 778 (03) : 549 - 558
[9] WALLMARK B, 1980, J BIOL CHEM, V255, P5313
[10] ON REVERSIBILITY OF BINDING OF CARDIOTONIC STEROIDS TO A PARTIALLY PURIFIED (NA+K)-ACTIVATED ADENOSINETRIPHOSPHATASE FROM BEEF BRAIN
YODA, A
HOKIN, LE
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1970, 40 (04) : 880 - &