THE CONVERSION OF ALPHA-HYDROXY ESTERS TO BETA-HYDROXY ESTERS BY A DEOXYGENATION CONDENSATION REACTION PROMOTED BY SAMARIUM DIIODIDE

被引：21

作者：

ENHOLM, EJ

JIANG, SJ

机构：

[1] Department of Chemistry, University of Florida, Gainesville

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 03期

基金：

美国国家科学基金会;

关键词：

SAMARIUM DIIODIDE; DEOXYGENATION; KETYL; BETA-ALKOXY ESTER;

D O I：

10.1016/S0040-4039(00)74119-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A mild reaction sequence begins by transforming an alpha-hydroxy ester to an alpha-benzoate ester. Next, the alpha-benzoate ester is both reductively deoxygenated with samarium diiodide and subsequently condensed with a ketone present in the reaction mixture to afford a beta-hydroxy ester with two new alkyl appendages.

引用

页码：313 / 316

页数：4