MODULATION OF MAMMALIAN O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE INVIVO BY O-6-BENZYLGUANINE AND ITS EFFECT ON THE SENSITIVITY OF A HUMAN GLIOMA TUMOR TO 1-(2-CHLOROETHYL)-3-(4-METHYLCYCLOHEXYL)-1-NITROSOUREA

被引：121

作者：

DOLAN, ME

STINE, L

MITCHELL, RB

MOSCHEL, RC

PEGG, AE

机构：

[1] NCI,FREDERICK CANC RES & DEV CTR,FREDERICK,MD 21702

[2] PENN STATE UNIV,MILTON S HERSHEY MED CTR,COLL MED,DEPT CELLULAR & MOLEC PHYSIOL,HERSHEY,PA 17033

[3] PENN STATE UNIV,MILTON S HERSHEY MED CTR,COLL MED,DEPT PHARMACOL,HERSHEY,PA 17033

来源：

CANCER COMMUNICATIONS | 1990年 / 2卷 / 11期

关键词：

D O I：

10.3727/095535490820873985

中图分类号：

学科分类号：

摘要：

[No abstract available]

引用

页码：371 / 377

页数：7

共 44 条

[1] INHIBITION OF O-6-ALKYLGUANINE-DNA-ALKYLTRANSFERASE ACTIVITY POTENTIATES CYTOTOXICITY AND INDUCTION OF SCES IN HUMAN GLIOMA-CELLS RESISTANT TO 1,3-BIS(2-CHLOROETHYL)-1-NITROSOUREA
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[4] FORMATION OF COVALENT COMPLEXES BETWEEN HUMAN O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE AND BCNU-TREATED DEFINED LENGTH SYNTHETIC OLIGODEOXYNUCLEOTIDES
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[7] DEXTER EU, 1989, CANCER RES, V49, P3520
[8] DOLAN ME, 1985, CANCER RES, V45, P6413
[9] DEPLETION OF O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE ACTIVITY IN MAMMALIAN-TISSUES AND HUMAN-TUMOR XENOGRAFTS IN NUDE-MICE BY TREATMENT WITH O-6-METHYLGUANINE
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[J]. CANCER CHEMOTHERAPY AND PHARMACOLOGY, 1989, 25 (02) : 103 - 108
[10] DOLAN ME, 1988, CANCER RES, V48, P3603

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