A NEW AND EFFICIENT PREPARATION OF CYCLIC CARBODIIMIDES FROM BIS(IMINOPHOSPHORANES) AND THE SYSTEM BOC(2)O/DMAP

被引：36

作者：

MOLINA, P ^{[1
]}

ALAJARIN, M ^{[1
]}

SANCHEZANDRADA, P ^{[1
]}

ELGUERO, J ^{[1
]}

JIMENO, ML ^{[1
]}

机构：

[1] CSIC, INST QUIM MED, E-28006 MADRID, SPAIN

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1994年 / 59卷 / 24期

关键词：

D O I：

10.1021/jo00103a022

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-pot synthesis of cyclic carbodiimides which involves reaction of C,C-bis(aryliminophosphoranes) connected by aliphatic bridges with Boc(2)O in the presence of DMAP is described. The method is also applicable when a heteroatom such as oxygen or nitrogen is incorporated into the tether connecting the two aromatic rings. A conformation study has been carried out on carbodiimide 23a, which posseses a central nine-membered ring, using H-1 NMR spectroscopy and semiempirical as well as molecular mechanics calculations.

引用

页码：7306 / 7315

页数：10