ENANTIOSELECTIVE CONJUGATE ADDITION OF ORGANOCUPRATE USING A CHIRAL AMIDOPHOSPHINE LIGAND

被引：46

作者：

KANAI, M

KOGA, K

TOMIOKA, K

机构：

[1] OSAKA UNIV,INST SCI & IND RES,IBARAKI,OSAKA 567,JAPAN

[2] UNIV TOKYO,FAC PHARMACEUT SCI,BUNKYO KU,TOKYO 113,JAPAN

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 47期

关键词：

D O I：

10.1016/S0040-4039(00)60870-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Based on the concept of a metal differentiating coordination, a new chiral amidophosphine ligand 2 was designed synthesized, and applied in an enantioselective conjugate addition of lithium dimethylcuprate to chalcone providing the corresponding adduct in 84% ee.

引用

页码：7193 / 7196

页数：4