DEXAMETHASONE PARTIALLY REDUCES AND 2-PERCENT SALINE-TREATMENT ABOLISHED ELECTRO-ACUPUNCTURE ANALGESIA - THESE FINDINGS IMPLICATE PITUITARY ENDORPHINS

被引：48

作者：

CHENG, R

POMERANZ, B

YU, G

机构：

[1] Department of Zoology, University of Toronto, Toronto

来源：

LIFE SCIENCES | 1979年 / 24卷 / 16期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/0024-3205(79)90031-6

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Dexamethasone, a cortisol analogue which inhibits ACTH and endorphin release in a negative feedback system, partially reduces electroacupuncture analgesia (EAA) in mice. In addition, mice forced to drink 2% saline for 3 days (this reduces pituitary endorphin levels) had a complete loss of EAA. These two experiments support our previous finding that hypophysectomy abolishes EAA. Altogether, these results implicate pituitary endorphins in EAA. © 1979.

引用

页码：1481 / 1486

页数：6

共 20 条

[11] EFFECT OF DEHYDRATION ON ENDOGENOUS OPIATE CONTENT OF RAT NEURO-INTERMEDIATE LOBE
MATA, MM
GAINER, H
KLEE, WA
[J]. LIFE SCIENCES, 1977, 21 (08) : 1159 - 1162
[12] ANTAGONISM OF ACUPUNCTURE ANALGESIA IN MAN BY NARCOTIC-ANTAGONIST NALOXONE
MAYER, DJ
PRICE, DD
RAFII, A
[J]. BRAIN RESEARCH, 1977, 121 (02) : 368 - 372
[13] NALOXONE BLOCKADE OF ACUPUNCTURE ANALGESIA - ENDORPHIN IMPLICATED
POMERANZ, B
CHIU, D
[J]. LIFE SCIENCES, 1976, 19 (11) : 1757 - 1762
[14] ACUPUNCTURE REDUCES ELECTROPHYSIOLOGICAL AND BEHAVIORAL-RESPONSES TO NOXIOUS STIMULI - PITUITARY IS IMPLICATED
POMERANZ, B
CHENG, R
LAW, P
[J]. EXPERIMENTAL NEUROLOGY, 1977, 54 (01) : 172 - 178
[15] POMERANZ B, 1977, NEW SCI, V73, P12
[16] FOOT-SHOCK INDUCED STRESS INCREASES BETA-ENDORPHIN LEVELS IN BLOOD BUT NOT BRAIN
ROSSIER, J
FRENCH, ED
RIVIER, C
LING, N
GUILLEMIN, R
BLOOM, FE
[J]. NATURE, 1977, 270 (5638) : 618 - 620
[17] ROSSIER J, 1978, SOC NEUR ABSTR, V4, P414
[18] SANTAGOSTINO A, 1978, ADV BIOCH PSYCHOPHAR, V18, P171
[19] THE STEROID FEEDBACK MECHANISM
SCHAPIRO, S
MARMORSTON, J
SOBEL, H
[J]. AMERICAN JOURNAL OF PHYSIOLOGY, 1958, 192 (01): : 58 - 62
[20] INCREASED CEREBROSPINAL-FLUID LEVELS OF ENDORPHINS AFTER ELECTRO-ACUPUNCTURE
SJOLUND, B
TERENIUS, L
ERIKSSON, M
[J]. ACTA PHYSIOLOGICA SCANDINAVICA, 1977, 100 (03): : 382 - 384

← 1 2 →