TOTAL SYNTHESIS OF THE POLYENE MACROLIDE ANTIBIOTIC ROXATICIN .1. SYNTHESIS OF THE POLYOL FRAGMENT OF ROXATICIN USING A 4-CARBON CHAIN EXTENSION STRATEGY

被引：45

作者：

MORI, Y

ASAI, M

OKUMURA, A

FURUKAWA, H

机构：

[1] Faculty of Pharmacy, Meijo University, Tempaku, Nagoya, 468

来源：

TETRAHEDRON | 1995年 / 51卷 / 18期

关键词：

D O I：

10.1016/0040-4020(95)00214-S

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The C11-C26 polyol fragment of roxaticin containing eight chiral centers has been prepared in a reiterative manner using coupling reactions of chiral dithianes and epoxides followed by stereoselective reduction.

引用

页码：5299 / 5314

页数：16