KINETIC RESOLUTION OF RAC-3-(2-METHYLPHENOXY)PROPANE-1,2-DIOL (MEPHENESIN) BY SEQUENTIAL LIPASE-CATALYZED TRANSESTERIFICATION

被引：35

作者：

THEIL, F

BALLSCHUH, S

KUNATH, A

SCHICK, H

机构：

[1] Central Institute of Organic Chemistry, 0-1199 Berlin-Adlershof

来源：

TETRAHEDRON-ASYMMETRY | 1991年 / 2卷 / 10期

关键词：

D O I：

10.1016/S0957-4166(00)86153-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The kinetic resolution of rac-3-(2-methylphenoxy)propane-1,2-diol (rac-1, Mephenesin) by sequential lipase-catalyzed transesterification with vinyl acetate in tetrahydrofuran/triethylamine in the presence of lipase Amano PS is described.

引用

页码：1031 / 1034

页数：4

共 21 条

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