BASAL AND REACTIVE PLASMA-CATECHOLAMINE LEVELS UNDER STRESS AND ANESTHESIA IN RABBITS

被引：11

作者：

DUAN, YF ^{[1
]}

WINTERS, RW ^{[1
]}

MCCABE, PM ^{[1
]}

GREEN, EJ ^{[1
]}

SCHNEIDERMAN, N ^{[1
]}

机构：

[1] UNIV MIAMI,DEPT PSYCHOL,CORAL GABLES,FL 33124

来源：

PHYSIOLOGY & BEHAVIOR | 1994年 / 56卷 / 03期

关键词：

PLASMA CATECHOLAMINE; DEFENSE REACTION; HYPOTHALAMUS; TILT STRESS; BAROREFLEX; PENTOBARBITAL; ISOFLURANE; RABBITS;

D O I：

10.1016/0031-9384(94)90304-2

中图分类号：

B84 [心理学];

学科分类号：

04 ; 0402 ;

摘要：

The present study was undertaken to determine if electrical stimulation of the hypothalamic defense area (HDA) and baroreflex activation elicited by head up body tilt produced changes in plasma catecholamine (CA) levels in anesthetized rabbits. We also compared the effects of two anesthetics, isoflurane and sodium pentobarbital, upon basal and reactive CA levels, and upon autonomic reactivity. HDA stimulation was found to produce significant increases in plasma norepinephrine (NE) levels but not epinephrine (E) levels. Passive tilt was found to produce statistically significant increases in NE Levels for both anesthetics used and a significant increase in E levels for animals anesthetized with isoflurane. Basal and reactive measurements provided evidence that pentobarbital has a more suppressive effect upon the autonomic nervous system than isoflurane: (a) Basal NE levels were significantly lower in pentobarbital-anesthetized animals than in isoflurane-anesthetized animals; and (b) Baroreceptor sensitivity to a passive tilt stressor was significantly higher for animals anesthetized with isoflurane than for animals anesthetized with pentobarbital.

引用

页码：577 / 583

页数：7

共 55 条

[21] PARTICIPATION OF ANTERIOR HYPOTHALAMUS IN BARORECEPTOR REFLEX [J].