1,4-ADDITION OF AZIDE TO TRANS-DIEPOXYCYCLOPENTANE WITH SOLVENT PARTICIPATION

被引：5

作者：

FARKAS, F

SEQUIN, U

BUR, D

ZEHNDER, M

机构：

[1] UNIV BASEL,INST ORGAN CHEM,ST JOHANNS RING 19,CH-4056 BASEL,SWITZERLAND

[2] UNIV BASEL,INST ANORGAN CHEM,CH-4056 BASEL,SWITZERLAND

来源：

TETRAHEDRON | 1992年 / 48卷 / 01期

关键词：

1,2-3,4-DIEPOXIDES; 1,4-ADDITION; AZIDOHYDRINS; NUCLEOPHILIC OPENING OF EPOXIDES;

D O I：

10.1016/S0040-4020(01)80582-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of trans-diepoxycyclopentane with azide leads in methanol to the expected azidohydrins; a 1,4-adduct with a 'central' epoxy group is also formed. When the reaction is carried out in acetone/water 1:1, an additional product, which is the acetonide of an azido-trihydroxycyclopentane, is observed. This compound must have been formed by participation of the solvent followed by cyclization.

引用

页码：103 / 110

页数：8

共 11 条

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