CHARACTERIZATION OF AN IMIDAZOLIUM COMPOUND FORMED BY REACTION OF METHYLGLYOXAL AND N-ALPHA-HIPPURYLLYSINE

被引：57

作者：

BRINKMANN, E ^{[1
]}

WELLSKNECHT, KJ ^{[1
]}

THORPE, SR ^{[1
]}

BAYNES, JW ^{[1
]}

机构：

[1] UNIV S CAROLINA,SCH MED,COLUMBIA,SC 29208

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1995年 / 22期

关键词：

D O I：

10.1039/p19950002817

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The 1,3-di-N-alpha-hippuryllysino-4-methylimidazolium salt 6 has been identified as a major product of reaction of the alpha-dicarbonyl compound, methylglyoxal 1, with the lysine derivative, N-alpha-hippuryllysine (N-alpha-benzoylglycyllysine) 2, in phosphate buffer at neutral pH, suggesting a mechanism for crosslinking of protein by 1 and related dicarbonyl compounds during the Maillard reaction.

引用

页码：2817 / 2818

页数：2

共 7 条

[1] HETEROCYCLIC BETAINES - PYRIDINIUM (IMIDAZOLIUM) AZOLATE INNER SALTS WITH SEVERAL INTERANNULAR LINKAGES [J].