GLUCOSE VERSUS GLUCOSE-FAT MIXTURE IN THE COURSE OF TOTAL PARENTERAL-NUTRITION - EFFECTS ON SUBSTRATE UTILIZATION AND ENERGY-METABOLISM IN MALNOURISHED CHILDREN

被引：12

作者：

SALAS, J ^{[1
]}

GIRARDET, JP ^{[1
]}

DEPOTTER, S ^{[1
]}

MARTIHENNEBERG, C ^{[1
]}

GOULET, O ^{[1
]}

RICOUR, C ^{[1
]}

机构：

[1] HOP NECKER ENFANTS MALAD,DEPT PEDIAT,SERV GASTROENTEROL & NUTR,149 RUE SEVRES,F-75730 PARIS 15,FRANCE

来源：

CLINICAL NUTRITION | 1991年 / 10卷 / 05期

关键词：

D O I：

10.1016/0261-5614(91)90006-X

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Energy substrate utilisation was evaluated over 21 days in two groups of malnourished children on total parenteral nutrition (TPN). Non-protein energy was infused as glucose (Group A; n = 7) or as a glucose/fat (1:1 v/v) mixture (Group B; n = 10). Results indicated that: 1) net glucose oxidation was related to glucose intake; 2) glucose storage was elevated in group A; 3) net fat synthesis occurred earlier in group B together with constant net fat oxidation which was inversely related to glucose intake (r = -0.89, p < 0.001); 4) lipogenesis from glucose occurred only when glucose intake exceeded 19.3 g/kg/d; 5) energy expenditure increased by 36% (group A) and 18% (group B) during renutrition; 6) 73% and 82% of the energy administered in excess of energy required was stored in group A and B respectively. Hence, glucose/fat infusion appears to be more energy-efficient than glucose-alone in TPN of malnourished children.

引用

页码：272 / 278

页数：7

共 24 条

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