PROPAGATION PATTERNS OF TEMPORAL SPIKES

被引:91
作者
EMERSON, RG
TURNER, CA
PEDLEY, TA
WALCZAK, TS
FORGIONE, M
机构
[1] Department of Neurology, Columbia University, Neurological Institute, New York, NY 10032
来源
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY | 1995年 / 94卷 / 05期
关键词
SPIKES; TEMPORAL LOBE; PROPAGATION; AVERAGING;
D O I
10.1016/0013-4694(94)00316-D
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
In standard EEG recordings, spikes appear as single events characterized mainly by the scalp location of the their peak voltage. The signal-to-noise ratio of raw EEG is usually too high to permit more detailed analysis. We used spike averaging to improve the resolution of interictal spikes in 40 patients with temporal lobe epilepsy. Spikes were identified visually in raw, digitally stored EEG. When multiple spike types were present in a patient, they were grouped separately. Spikes were synchronized for averaging by aligning their negative peaks in a designated channel. Sixteen patients demonstrated spike propagation from anterior temporal to posterior temporal electrode locations. Thirty-six patients demonstrated spread of spikes from anterior temporal to fronto-polar electrode sites. While anterior temporal and fronto-polar spikes were often synchronous, fronto-polar spikes followed anterior temporal discharges in 25% of cases and preceded them in 13%. Spike averaging revealed propagation patterns not apparent on visual inspection of raw EEG. We speculate that these patterns may reflect inherent physiological properties of temporal and frontal neuronal circuits, possibly utilized by the epileptogenic process.
引用
收藏
页码:338 / 348
页数:11
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